Sickle Cell Anemia
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The sickle cell disease is an inheritable blood disease which occurs when a person inherits two abnormal genes, one from each parent, that cause their red blood cells to change shape. Instead of being flexible and round, these cells are more rigid and curved like a banana, a holly leaf or a sickle. This impairs their passage through the small blood vessels. Since red blood cells are very important in delivering oxygen to all the body, many organs can be affected along with their growth.
Moreover, sickling causes a decrease of oxygenation and blood flow. As a result this could generate painful crisis such as headaches or pain and growth defects. In the severe form, these crises can cause damage to the lungs, kidneys, liver and bones and bring about leg ulcers and blindness.
There is no cure for sickle cell disease. Basic treatment includes heavy pain-killing drugs and oral and intravenous fluids to reduce pain. Blood transfusions are used to treat some complications. There are things that have shown to provide a cure for severe patients; this includes bone marrow transplantation and gene therapy.
For more info:
American Sickle Cell Anemia Association
www.ascaa.org
(216) 229-8600
Sickle Cell Disease Association of America
www.sicklecelldisease.org
(800) 421-8453
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