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Global Health Watch
BACKGROUND REPORT  MARCH 19, 2009

Cardiovascular diseases


Cardiovascular diseases, also known as heart disease, often involve the narrowing or blockage of blood vessels that can lead to a heart attack or stroke. Heart disease also includes high blood pressure, conditions that affect the heart's muscle, valves or function, as well as malformations of the heart's structure that exist at birth.

The most common type is coronary heart disease, which occurs when the coronary arteries supplying blood to the heart become hardened and narrowed, which can cause heart attacks. Cerebrovascular disease affects the blood vessels that supply the brain and can cause stroke.

Global Impact

Cardiovascular diseases are the No. 1 cause of death in the world. An estimated 17.5 million people died from heart disease in 2005, representing 30 percent of all global deaths. About 80 percent of these deaths occurred in poor and middle-income countries, according to the World Health Organization.

Heart attacks and strokes are the biggest contributors to deaths from heart disease.

Cardiovascular diseases can take a significant financial toll on populations and countries due their prevalence and often huge out-of-pocket health expenses for many families.

Causes

Blockages that prevent blood from flowing to the heart or the brain are the primary causes of heart disease, heart attack and strokes. Fatty deposits can build up on the inner walls of arteries, which are blood vessels that carry blood, oxygen and nutrients to the heart, brain and the rest of the body. The buildup of fatty plaques narrows the blood vessels and makes them less flexible. Over time, this can cause hardening of the arteries.

When a blood vessel becomes blocked by a clot, it can't deliver blood, which could cause damage to the heart or the brain.

Major risk factors in cardiovascular disease include an unhealthy diet, lack of exercise, being overweight and smoking.

Symptoms

There are often no symptoms that accompany cardiovascular disease until the onset of a serious incident such as a heart attack or stroke.

Prevention

Lifestyle changes can help prevent cardiovascular disease, including quitting smoking, exercising regularly, eating healthy foods and reducing stress.

Treatment

Cardiovascular disease can be treated with medication or medical procedures, but often involves bringing lifestyle habits in line through a low-fat, low-sodium diet and regular exercise. Medications can be prescribed to help lower high blood pressure, or lower cholesterol.

In more serious cases, surgery may be recommended to relieve chest pain and open a blockage. Coronary angioplasty, the most common surgery, is performed by threading a small balloon into a blocked artery and inflating it to reopen the passageway. A small metal coil called a stent is often inserted to keep the artery open.

Another common surgery is a coronary artery bypass, in which the blocked portion of an artery is removed and replaced with part of a vein from another part of the body.

Sources: National Heart Blood and Lung Institute, Mayo Clinic, CDC, National Institutes of Health, U.S. National Library of Medicine and The World Health Organization.

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