Visit Your Local PBS Station PBS Home PBS Home Programs A-Z TV Schedules Watch Video Support PBS Shop PBS Search PBS

TV Schedule
Alan Alda
For Educators
Previous Shows
Future Shows
Special Features

Body Building
Body on a Bench
 
. .
Stem Cells 101 3 pages: | 1 | 2 | 3 |

An "Ethical Minefield"

Photo of President Bush
President Bush announced his stem cell research policy on August 9, 2001.

On August 9th, 2001, President Bush announced that his administration would ban federal funding of human embryonic stem cell research, characterizing the embryos these cells come from as "the seeds of the next generation." But, acknowledging that "research offers hope that millions of our loved ones may be cured of a disease and rid of their suffering," Bush also said he would allow funding research on the sixty lines of stem cells already harvested by private researchers. (Click here to read this speech)

Bush's careful compromise pleased neither anti-abortion advocates nor researchers. To the first group, using any product derived from destroyed human fetuses constitutes a shocking disrespect for human life. According to the American Life League, Bush's decision "condones the act of direct killing and creates a situation whereby the federal government becomes complicit in the act that originally took the life of each of those hundreds of embryonic beings who were killed in order to develop the stem cell lines."

 

Bush's careful compromise pleased neither anti-abortion advocates nor researchers.

Stem cell researchers, on the other hand, believe the withholding of federal funds could mean the promise of stem cell research will never come to fruition. Scientists believe the Bush compromise will slow research for several reasons. First, researches say the 60 already established stem cell lines Bush made eligible for federal funding won't be adequate.

"A stem cell grown for many generations isn't very useful anymore," says Melton. "The potential to differentiate into all cell types is degraded or lost," says Melton. "The other problem is that they accumulate mutations."

Image of Retinal Cells
Scientists have had success using stem cells to grow new retina cells on special scaffolds implanted in rats. It's not yet clear if the new cell growth improved the rats' vision.

Of those 60 lines, Melton estimates only 20 are still able to give rise to useful cells. Of those, about half are owned by private companies or foreign countries, neither of which are under any obligation to share their wealth with American government researchers. Of the handful remaining, some simply don't work. They don't propagate new cells, and researchers do not yet know why.

"While, this number 60 seems stuck in everyone's head, the number is definitely less than ten," says Melton. "So there is an insufficient number."

In his August 2001 remarks, Bush left the door open for private foundations and corporations to obtain and experiment on embryonic stem cells. But researchers argue that private moneys will never match government funding. Even if it could, some say there might not be any researchers to do the experimental work.

"Because of all of the signals from our federal government, young people seem to be frightened to enter this field," says Melton. "They fear that it will not be aggressively funded in the future."

And these fears may be valid. On April 10th, 2002, Bush called on the Senate to pass legislation banning the cloning of human embryos - for both reproductive and research purposes. (Click here to read this speech)

 

This type of therapy could mean the end of countless other diseases such as Parkinson's, Alzheimer's, and osteoporosis, to name just a few.

Since cloning is one source of embryonic stem cells, banning the procedure would slow progress in the field significantly. Such legislation will likely meet tough opposition on both sides of the aisle in Congress, but the Bush administration's wariness towards stem cell research is in stark contrast to the more liberal policies recently adopted in the U.K., Australia and other nations. U.S. researchers worry that America's best and brightest minds might be forced to continue their work abroad. Scientists like Melton caution against this so-called "reverse brain drain."

"There are certain things that are in your national interest and healthcare is one of them," Melton argues. "Why does the defense department pay U.S. contractors to develop guns and bombs? Why not let other nations do that? Because it's not in our national interest, that's why."
- - - - - - - - - - - -
3 pages: | 1 | 2 | 3 |

return to show page
photo: White House photo by Eric Draper

 

 

How to Make A NoseBody on a BenchSearch for the Perfect HeartNerves of Steel Teaching guide Science hotline video trailer Resources Contact Search Homepage