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Make Up Your Mind
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Frontiers Profile: Adele Diamond

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By Jacqueline S. Mitchell

Photo of Child at ComputerOctober 15, 2002
"This is our very best room," Dr. Adele Diamond says proudly, opening the door to the mother of all waiting rooms. Primary colors assault the eyes. Marbles make music tripping their way down a painted wooden spiral. Five-year-old Thomas spills out the pieces to a foam puzzle on the floor while his mother fills out a questionnaire. "Thomas, pretend like you're kicking a soccer ball," she asks. The boy stands up - grinning wickedly - and pantomimes a fierce kick. "Thank you," his mother says, then mutters "Right foot," as she turns her attention back to the clipboard on her lap.
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Reading Minds

Though he's perfectly healthy, Thomas is here to have his brain scanned. He's one of 40 five- and eight-year-olds who will visit Diamond's lab this week. A researcher at the Eunice Kennedy Shriver Center at the University of Massachusetts School of Medicine in Waltham, Diamond hopes her experiment will help refine the art of reading little kids' minds.


Diamond hopes her experiment will help refine the art of reading little kids' minds.

As we saw in "Why Kids Don't Get It," Diamond studies the development of children's frontal lobes, the part of the brain responsible for higher cognitive tasks. Much of her work requires children to perform cognitive tasks while lying still in an fMRI, or functional magnetic resonance imaging machine. The resulting snap-shot indicates which parts of the brain are active during specific cognitive tasks.

Photo of Girl in Mock Scanner  
Does trying to lie still affect data from children's brain scans?

But Diamond wondered if the very act of remaining still -that is, inhibiting all the wiggles and squirminess of youth- takes such brain power that it affects the data from the fMRI. Additionally, there's evidence that adults and children show some differences in performing cognitive tasks depending on whether they are upright or lying down. Diamond wonders if results obtained from children lying down in an fMRI machine are similarly affected. To get to the bottom of these questions, Diamond - joined by Dr. Dennis Molfese, chair of the Developmental Neuropsychology at the University of Louisville - will ask Thomas and the 39 other boys and girls to play a computer game.

Circles and Stripes

"I have more computer games than my sister," Thomas tells Eva Ratajczak one of Molfese's two undergraduate assistants, as she leads him to the lab where the team has built a pretend FMRI. Essentially a doctor's exam table placed in front of a hole in a brightly painted wall, the mock-up doesn't look much like the hi-tech medical instrument it's supposed to be. But the lack of detail doesn't matter at all to Thomas, whom lab assistant Jamie Wilson plunks down on the table in front of a computer screen. She also hands him a control box with two buttons.

The screen shows Thomas two kinds of circles, solid gray ones and striped ones. Circles of both types may appear on either the right or left side of the computer screen. When Thomas sees solid gray circles, he is supposed to click the button on the corresponding side of his control box. When Thomas sees striped circles, he is to click the button on the opposite side of the control box.

Photo of Thomas
The electrodes in this cap will measure Thomas' brain waves during the experiment.

After minimal coaching and heaps of motivational praise, Thomas is clicking away, making hardly any mistakes. But this is only a warm up. Once the researchers are confident Thomas understands the rules of this new game, the real testing begins. Wilson and Ratajczak guide Thomas into a prep room where they cover him in a smock then attach a cap of electrodes to his head.


"You see the same cognitive changes in babies in all different circumstances; Babies with multiple caregivers, babies with one caregiver, babies from poor families, rich families, American babies, African babies- it doesn't matter."

Crowned with real electrodes, Thomas returns to the room with the mock fMRI. He plays the computer game three more times- once sitting, once lying in the mock MRI, and once lying in the machine while trying to remain perfectly still. During each trial, the electrodes monitor his brain waves. Unlike a real fMRI, the electrode cap won't reveal which parts of Thomas' brain are involved in the task, but it will reveal differences in the quality of the data obtained during the three separate trials.

The trials take what seems like a long time for a five-year-old. Indeed, Thomas does get at times fidgety, at other times dangerously close to falling asleep, as indicated by the alpha waves scrolling across the computer screen. At last- just under two hours after he arrived - Thomas is leaving the lab, but not before choosing a small reward from the lab's "supply closet," filled with stickers, bean bag toys and other small objects.
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Images: Diamond Lab

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