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Make Up Your Mind
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. Web Feature .
Of Bumps and Brains
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By Jacqueline S. Mitchell

Photo of Alan  and Dr. Ratieu examine Gage's SkullOctober 15, 2002
I
n "Make Up Your Mind," scientists attempt to reconstruct the injuries sustained by Phineas Gage on September 13th, 1848. Gage was a twenty-five-year-old railroad foreman when a blasting accident drove a three-foot-long iron spike clear through Gage's skull. The rod entered just below Gage's left cheek and exited out the top of his head, landing some 25 yards away smeared with blood and brain matter.

Remarkably, Gage's wounds were not fatal. In fact, he never even lost consciousness. Though it would take him several months to recover from the injuries and subsequent infections, Gage would live another twelve years, working to support himself. Yet his friends would recall that from that September day onward, Gage "was not Gage." Though his body healed, his personality had changed. The once-respected young man was now described as "fitful," "impatient and obstinate," and "grossly profane."

The extraordinary case of Phineas Gage was the first to make the connection between the brain and personality quite so clear. In "Make Up Your Mind," Alan meets scientists who study a range of human behaviors - from a baby's attempts to find a hidden toy, to an adult's ability to make life or death choices. Their goal is to determine which parts of the brain play a role in the decision-making process. Underlying this research is the presumption that different regions of the brain control different cognitive functions. Today's advanced imaging and modeling technologies provide ample evidence of this "functional localization," but the notion was a radical one when physiologists first began seriously studying the human brain more than two hundred years ago. It took a now-discredited pseudoscience to pave the way for today's sophisticated neuroscience.
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A Partitioned Mind

In 1810, Franz Josef Gall and his colleague Johann Spurzheim published their seminal work, "The Anatomy and Physiology of the Nervous System in General, and of the Brain in Particular." In it, Gall, a respected Austrian physician, laid out the fundamentals of the science he called "Cranioscopy," which correlated external physical features of the skull to personality traits.


As a youth, Gall noticed that that physical features seemed to reflect emotional and intellectual qualities.

Gall had been ruminating on the notion that physical features reflected emotional and intellectual qualities since he was a youth. He noticed that students with large eyes seemed to have more academic aptitude than their smaller-eyed peers. Later, as a student of medicine, Gall began taking skull measurements of friends, colleagues and patients. From his careful analyzed data, Gall developed detailed skull charts.

Image of Skull Chart
Gall believed features of the skull revealed character traits of individuals.  

Gall believed he'd found a region on the skull that correlated to each of 27 personality traits, ranging from musical talent to mathematical ability to "Theosophy," or one's sense of God and religion. The shape of the head and the size of each specific region of the skull - measured with the hands or calipers, then compared to Gall's head charts - indicated the relative development of each trait. A full cranioscopy, somewhat akin to an astrological reading, would reveal one's true personality, help one discover strengths and weakness, and take the mystery out of who might make a compatible spouse or business partner.

Though Galls' head charts would eventually fall out of scientific favor, this notion of functional localization opened the door for modern neuroscience. All of Gall's work rested on the assumption not only that the brain is the organ of the "mind" or personality, but also that the brain itself is organized into smaller sections, each responsible for separate talents and tendencies.


Gall's ideas so offended the sensibilities of the day, that Gall was forced to leave his native Austria in 1805.

When Gall began publicly lecturing on cranioscopy in 1796, this was a conceptual leap many of Gall's contemporaries were not ready to make.

"Historically, for hundreds of years -maybe from the medieval period even - there was the belief that the "mind" and soul could not be partitioned," says Robert H. Wozniak, professor of Psychology at Bryn Mawr College in Pennsylvania. "It came from a variety of theological beliefs."

In fact, Gall's ideas so offended the sensibilities of the day, that Gall was forced to leave his native Austria in 1805. Gall and his German protégé Spurzheim traveled for two years before settling in Paris. Ironically, their exile and subsequent wanderings would only ensure Gall's new science would catch on all over western Europe and the United States.
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