In Gaskell's Words: Mrs. Hamley

He had married a delicate fine London lady; it was one of those perplexing marriages of which one cannot understand the reasons. Yet they were very happy, though possibly Mrs. Hamley would not have sunk into the condition of a chronic invalid, if her husband had cared a little more for her various tastes, or allowed her the companionship of those who did... Mrs. Hamley was a great reader, and had considerable literary taste. She was gentle and sentimental; tender and good. She gave up her visits to London; she gave up her sociable pleasure in the company of her fellows in education and position. Her husband, owing to the deficiencies of his early years, disliked associating with those to whom he ought to have been an equal; he was too proud to mingle with his inferiors. He loved his wife all the more dearly for her sacrifices for him; but, deprived of all her strong interests, she sank into ill-health; nothing definite; only she never was well.

Wives and Daughters
Chapter IV, Mr. Gibson's Neighbors