Part 1
Sleuthing surgeon Dr. Joseph Bell (Ian Richardson) taps medical student Arthur Conan Doyle (Robin Laing) to help with Bell's undercover work for the Edinburgh police. His deductive methods crack one especially difficult case and set young Doyle thinking about another -- one that everybody, Bell included, has discounted as an unsuspicious death.

Part 2

Called in to treat Lady Sarah Carlisle (Ruth Platt), Dr. Bell and Doyle discover she has syphilis, which leads them to Edinburgh's seamy underworld and evidence connecting a series of murders to a surprising suspect. Complicating the plot are Doyle's fellow medical students: the beguiling beauty Elspeth (Dolly Wells), the religious fanatic Crawford (Joel Strachan), and the manic American Neill (Alec Newman).

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