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Faces of Science: Nicole Le Douarin

Mariana Cook’s book, “Faces of Science,” portrays 77 scientists who have made many of the most important discoveries of our time. Each photograph is accompanied by a personal essay written by the scientists. The portraits in this online series are accompanied by excerpts from those essays. For more information, please visit Mariana Cook’s website:

Nicole Le Douarin - Photos and Text ©Mariana Cook “Faces of Science”

As a scientist, you have to be in agreement with what you observe and not with what you think beforehand. I have always been interested in the development of the embryo because it is fascinating to me that a single cell can give rise to such a complex organism as a human being. I like the challenge and the call on the imagination required by research.

I grew up in Britain, where my mother was a school-teacher and I was one of her pupils in elementary school. I am immensely grateful for the education she gave me. Throughout my childhood and adolescence, her example inspired me and gave me the ambition to learn and to try and understand the complexity of the world.

My scientific activity has been devoted to studying the embryogenesis of the nervous and immune systems. Through my work, I have learned that certain cells which will form the embryo display a very special behavior because they move away from the place in which they originate to contribute to distant tissues. This typical feature was not fully realized before I devised a technique which allows us to follow the migration and fate of embryonic cells throughout development. Applying this cell-marking technique, based on the construction of chimeras (which means associating cells from two different species whose cells can be recognized) in an avian embryo, sheds light on unsuspected events, which are crucial in the fields of cell and development biology as well as in evolutionary biology.

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Mariana Cook

    MARIANA COOK is a fine art photographer whose work is held in numerous institutional and private collections, including The Metropolitan Museum of Art and The Museum of Modern Art, New York City; The J. Paul Getty Museum, Los Angeles; The Museum of Fine Arts, Boston; The Museum of Fine Arts, Houston; Bibliothèque Nationale and Musée d’Art Moderne de la ville de Paris; and the National Portrait Gallery, Washington, DC. Ten books of her work have been published, including the best-selling Fathers and Daughters (1994) and the most recent, Justice: Faces of the Human Rights Revolution (2013). Stone Walls: Personal Boundaries was her first book of landscapes, which was released in 2011 to much acclaim. Her website is