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With the advent of Jane Seymour, Mary was finally reconciled with her father - but at a price. After much pressure, Mary signed documents recognizing her parents' marriage as invalid and her father as head of the church in England. It was an action for which she would never forgive herself.
More challenges lay ahead - Edward VI disbarred his half-sister from the succession in favor of his Protestant cousin, Lady Jane Grey. After Mary
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overthrew this nine-day queen (and had her executed), she went on to a particularly unpopular reign as England's first woman ruler. She would be remembered as "Bloody Mary" for burning at the stake some 300 Protestants as heretics. Her marriage to her cousin Prince Philip of Spain would not be happy. She would also lose Calais, England's last continental land holding - a loss that would trouble her to her death.
After two phantom pregnancies, Mary finally died in 1558, possibly from cancer.
Ultimate Fate 
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