NOVA | Teachers | Ghost in Your Genes | Student Handout: Gene Locations on Array

Ghost in Your Genes

Student Handout

Gene Locations on Array

The following charts show which genes are represented by each spot on your array. Use the key on this page to determine the expression level of each gene for your patient. Then record whether each gene was strongly expressed (+), strongly repressed (-), or neither strongly expressed nor repressed (0) underneath the name of each gene.

Patient 1 Profile

	1	2	3	4	5	6	7	8
A	ESR1	ABC-C6	BCL2	DPYD	TOP2A	GSTP1	CDC2	GATA3
B	DHFR	EGFR	ERB-B2	ABC-B2	MT1	TGFB3	ANXA	GRB7

Patient 2 Profile

	1	2	3	4	5	6	7	8
A	ESR1	ABC-C6	BCL2	DPYD	TOP2A	GSTP1	CDC2	GATA3
B	DHFR	EGFR	ERB-B2	ABC-B2	MT1	TGFB3	ANXA	GRB7

Key
+ = overexpressed (dark pink)
- = underexpressed (light pink)
0 = normal (clear)

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