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NOVA scienceNOW: Anthrax Investigation

Program Overview


Follow FBI agents and scientists as they participate in one of the most extensive criminal investigations ever—to unravel the mystery of where the anthrax used in the 2001 attacks originated.

This NOVA scienceNOW segment:

  • chronicles the origin of the mystery—tabloid photo editor Robert Stevens was diagnosed as dying from inhalation of anthrax in the fall of 2001.

  • reveals how scientists identified Stevens's anthrax as matching the Ames strain from the United States Army Medical Research Institute of Infectious Diseases (USAMRIID).

  • notes that the anthrax threat grew when four mailed letters laced with anthrax turned up at news outlets and the U.S. Senate.

  • explains how The Institute for Genomic Research compared the entire genome of Stevens's anthrax with that of the Ames strain—more than 5 million letters and 5,000 genes—but found no differences.

  • recounts that silica, a substance used to make anthrax disperse more easily, was found in the anthrax samples used in the attacks.

  • shows how a scientist used a scanning electron microscope to determine that the silica was not used to weaponize the anthrax.

  • reports how researchers used information about "attack" anthrax colonies grown in the lab to find single-letter mutations in several strains, and then compared those to samples collected from labs that had worked with the Ames strain.

  • reveals the way that researchers and FBI agents traced the attack anthrax back to its original source, USAMRIID, where it was kept by scientist Bruce Ivins.

  • concludes by noting that this new area of science—microbial forensics may enable scientists to trace future infectious-disease outbreaks back to their origins, potentially stopping their spread.

Taping Rights: Can be used up to one year after the program is taped off the air.

Teacher's Guide
NOVA scienceNOW: Anthrax Investigation
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