Curriculum SupplementsGenes, Environment, and Human Behavior. Biological Sciences Curriculum
Study. Colorado Springs, CO, 2000.
A downloadable teaching module comprised of five student activities that lay
out the methods and assumptions of behavioral genetics. Focuses on some of the
complex interactions between the genetic, developmental, and environmental
factors governing human behavior, and prepares students to think about
implications for public policy. Available free in PDF format at: http://www.bscs.org/pdf/projects/HGN4/HGN-IV.pdf
Human Genetic Variation. National Institutes of Health (NIH), BSCS,
& Videodiscovery, Inc. Curriculum Supplement Series, NIH Publication No.
99-4647. October 1999.
For grades 9-12. Offers teachers five inquiry-based activities for students to
explore how scientific research in human genetic variation can yield more
targeted, and potentially more effective, medical treatments. Encourages
analysis of the ethical, legal, and social issues arising from genomic data.
Provides correlations to national science education standards, as well as tips
for student assessment. Available free from the NIH Office of Science Education at: http://science-education.nih.gov/supplements
BooksYour Genes, Your Choices: Exploring the Issues Raised by Genetic Research. By
Catherine Baker. Washington D.C.: The American Association for the Advancement
of Science, 1999.
Funded by the U.S. Department of Energy, this book uses specific cases to probe
analysis about the ethical, legal, and social implications of the Human Genome
Project. For a table of contents and more information, see: http://www.ornl.gov/hgmis/publicat/genechoice/index.html
Primer on Molecular Genetics.By Denise Casey. Human Genome
Project, U.S. Department of Energy. Washington, D.C., 1992.
Provides a glossary to Human Genome Project terms, as well as basic genetic
definitions. Also covers mapping and sequencing of the human genome, and
explains sequencing technologies, the search for specific genes, and the
challenges of data collection and interpretation. Ends with a section about the
impact of the Human Genome Project. Available on the Web at: http://www.ornl.gov/hgmis/publicat/primer/intro.html
The Human Genome Project: Cracking the Code Within Us. By Elizabeth L
Marshall. Minneapolis, MN: Econo-Clad Books, 1999.
Explores the process and technology used in sequencing a portion of the human
genome. Connects the discoveries in the human genome with their ethical
implications.
Abraham Lincoln's DNA and Other Adventures in Genetics. By Philip
R. Reilly. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, August
2000.
Draws from a wide range of tales of crime, history, illness, and ethics to
prompt reflection upon principles and issues in human genetics.
Rosalind Franklin and DNA. By Anne Sayre. New York, NY: W. W.
Norton & Co., Inc., July 2000.
Offers an account of Franklin's work elucidating the structure of DNA and
explores the difficulties often faced by women in science. (Franklin's research
played a critical role in the Nobel Prize-winning discovery of DNA; Watson and
Crick's discovery relied heavily on her X-ray crystallography data.)
The Double Helix: A Personal Account of the Discovery of the Structure of
DNA. By James D. Watson. New York, NY: Simon & Schuster,
1998.
Chronicles the race to discover the structure of DNA and some of the scientific
rivalries involved, as seen by James Watson.
ArticlesA Structure of Deoxyribonucleic Acid. By Francis Crick and James Watson.
Nature. Volume 171, 1953: 737-738.
The seminal paper on the discovery of the structure of DNA.
Outlook 2000: Inventing the Future. U.S. News & World Report.
January 3, 2000.
Special double issue features various articles about the Human Genome Project,
on topics ranging from how learning the secrets of DNA may help cure illnesses
and arrest aging to the benefits and perils of genetic testing.
Shows which diseases have been mapped on which chromosomes. The Map Viewer presents a
graphical view of the available human genome sequence data, as well as
cytogenetic, genetic, physical, and radiation hybrid maps.
Presents background on the Human Genome Project from the National Human Genome
Research Institute. Links to more detailed resources describing the history and
goals of the Human Genome Project.
Provides short answers to popular questions about gene therapy, such as "What
scientific developments led up to gene therapy?," "What major problems must
scientists overcome before gene therapy becomes a common technique for treating
disease?," and "What impact is gene therapy likely to have on medicine in the
future?" Discusses the basics of germ-line gene therapy and genetic
enhancement.
Outlines techniques commonly used by researchers, including chromosome
microdissection, DNA chip technology, DNA microarray technology, fluorescence
in situ hybridization, polymerase chain reaction, and spectral karyotyping.
Sponsored
by the U.S. Department of Energy, this site offers background on the Human
Genome Project, along with links to images, diagrams, an idea exchange for
science projects relating to the human genome, and information about careers in
genetics.
Includes a timeline with key genetic discoveries since 1953 and articles about
the basics in the Human Genome Project, the most recent clonings (piglets), and
applications of genetic research in the plant and animal realm. Also explores
the implications of genetic research and gene therapy for humans, providing
links to additional resources, as well as articles about business and ethical
considerations.