At Camp Lazear, a building was set up to provide optimum conditions for infection by each means of transmission. Seven tents for volunteers were placed on the site, guarded by military personnel.
The "infected clothing building," as the team called it, was set up with three beds and a stove, so that a warmer temperature could be replicated. Yellow fever outbreaks were consistent with warm, summer weather. A collection of bedding, clothing and towels soiled with blood and other excretions from infected yellow fever patients were spread about the room and placed on the beds.
The other building, dubbed the "mosquito building," was divided into two sections, separated by a wire screen partition. A mosquito breeding room was connected to the larger of the two sections, which also had one clean, sterile bed. Two beds were set up in the smaller section, which was isolated from the mosquito breeding room. As with the other building, the interior was kept warm. An open vessel of water was set up in the larger room to provide a breeding ground for mosquitoes.
Reed and his team assembled a group of volunteers consisting of Army personnel and Spanish immigrants. Each volunteer was paid $100 to participate and received an additional $100 if infected.
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