A 22-Tablet System
In 1962, Organon Laboratories in Holland developed Lyndiol, a birth control pill administered on a 22-tablet regimen. Unlike the "three weeks on, one week off" system, Organon reasoned that "maximum patient reliability" was achieved when each new cycle of tablets began and ended on the same day of the week. If the last tablet was taken on a Friday, the first tablet from the next package would be taken the next Friday.