Visit Your Local PBS Station PBS Home PBS Home Programs A-Z TV Schedules Watch Video Donate Shop PBS Search PBS

NOVA Online (click here for NOVA home)
Surviving AIDS
Site Map

Animation of HIV life cycle
Life Cycle of HIV

See the full Quicktime movie (10MB) | Get QuickTime

See HIV in Action

Dr. José Assouline, a neurobiologist and AIDS researcher at the University of Iowa College of Medicine, has spent several years creating the animations below. They graphically represent the life cycle of HIV-1, from the initial binding of the viral particle onto a host cell (Viral Entry), through insinuation into the host cell's nucleus to spark the formation of new viral RNA strands (Viral Gene Transfer), and finally to the creation and migration out of the cell of a new HIV particle, complete with two copies of viral RNA (Viral Exit).

The complete life cycle is shown below. To see each of the three steps more slowly, and to learn exactly what's happening in each, click on the three thumbnail images below.

Viral Entry thumbnail
Viral Entry
Viral gene transfer thumbnail
Viral Gene Transfer
Viral Exit thumbnail
Viral Exit

Search for a Vaccine | See HIV in Action | AIDS in Perspective
The Virus Fighters | Fighting Back | Help/Resources
Teacher's Guide | Transcript | Site Map | Surviving AIDS Home

Editor's Picks | Previous Sites | Join Us/E-mail | TV/Web Schedule
About NOVA | Teachers | Site Map | Shop | Jobs | Search | To print
PBS Online | NOVA Online | WGBH

© | Updated October 2000

Support provided by

For new content
visit the redesigned
NOVA site

Feedback Site Map NOVA