Frontline World

Hong Kong - Chasing the Virus, June 2003


Related Features THE STORY
Synopsis of "Chasing the Virus"

EPIDEMICS THROUGH TIME
Tracing Disease Outbreaks

INTERVIEW WITH RENATA SIMONE
On the Trail of a Killer

PEPTIDES, ANTIBODIES, MEMBRANES ... WHAT?
Scientists spell out their approach to SARS

LINKS & RESOURCES
International Health Organizations, Search for a Quick Cure, Economic Fallout

MAP

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Epidemics Through Time

Map of world

By Kelly Whalen

Get and update on infectious diseases today. GOIntroduction

When a mysterious pneumonia showed up in the southern Chinese province of Guangdong in November 2002, few could have predicted the global crisis it would cause. The outbreak is now known, of course, as severe acute respiratory syndrome, or SARS.

SARS, a coronavirus believed to have jumped from animals to humans, is something relatively rare -- a life-threatening disease that spreads from one person to another through casual contact. The disease has reached more than two dozen countries since the first case was identified. By June 2003, more than 8,400 people worldwide had been infected by SARS and more than 780 had died.

Although the death count pales when compared with outbreaks of other diseases throughout history, the swift spread of SARS raises strong concerns about the vulnerability we face in this age of globalization. During the initial months of the SARS outbreak, newspapers predicted that it was "the next AIDS." More doomsday prophecies followed as the realization set in that a deadly infectious virus can move from one corner of the world to another in less than a day, simply by hitching a ride on an unsuspecting airplane passenger.

Yet, even though illnesses can infect populations faster than ever before, the spread of infectious disease always has been linked to an increasing number of people moving around the world. Smallpox followed explorers during the age of exploration, and tuberculosis surfaced in overpopulated city centers during the Industrial Revolution. In this interactive world atlas, trace the spread of the SARS crisis and other key epidemics throughout history.

Click on each disease name on the map above to learn more about its outbreak and spread.



Malaria: In 95 B.C., malaria, a mosquito-borne disease, was so endemic to the swampy farmland outside the ancient city of Rome that it was called "Roman fever." Mosquitoes followed farmers who moved to the city, the epidemic flourished, and Rome's population dwindled.

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Plague: In 1347, Black Death, carried by rats and fleas, spread along old silk caravan and spice trading routes, killing nearly one-third of Europe's population in just four years.

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Smallpox: Half the population of the area now surrounding modern Mexico City died from smallpox in 1520. The disease was spread by Spanish conquistadors, and in its wake, two empires fell, the Aztecs in Mexico and the Incas in Peru.

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Tuberculosis: By 1815, one in four deaths in England were the result of a tuberculosis epidemic, or the Great White Plague. The airborne disease spread through rapid industrialization in overcrowded cities.

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Cholera: Widespread flooding and famine caused a cholera outbreak in 1817 in India. British industrialists and troops then carried the disease, via contaminated water and food, to the country's northern borders. Trading ships spread the disease east.

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Yellow Fever: In 1853, one in 10 people in New Orleans and 20,000 people along the Mississippi Delta were felled by yellow fever. The mosquito-borne disease, with origins in Africa, came to the United States on slave ships.

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Spanish Flu: In 1917, World War I U.S. army camps reported a flu death every hour. The deadly disease, spread at seaports, accounted for more lost lives than those killed on WWI battlefields.

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Hepatitis B: In 1942, more than 50,000 U.S. military personnel were hospitalized after an unexplained hepatitis B outbreak, the biggest ever recorded in the history of the disease. The epidemic was linked to tainted human serum in a yellow fever vaccination used on soldiers that had not yet been FDA-approved.

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AIDS:
After the initial outbreaks of AIDS in 1980, it took medical researchers three years to identify the retrovirus, HIV, that causes the disease. By then, the virus, which is transmitted through sexual intercourse and contaminated blood and hypodermic needles, had felled 1,000 people in the United States and had spread to dozens of other countries.

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SARS: In November 2002, a deadly virus never before seen in humans was reported in China's Foshan City. Scientists have since linked hundreds of cases around the globe to a cluster of people, including a medical professor who may have treated a victim of SARS, then stayed in a crowded Hong Kong hotel in February.

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Sources include: World Health Organization; Brent Hoff and Carter Smith III (and Charles H. Calisher as consulting editor), "Mapping Epidemics: A Historical Atlas of Disease," New York: Franklin Watts, a division of Grolier Publishing, 2000; Sheldon Watts, "Epidemics and History: Disease, Power and Imperialism," New Haven and London: Yale University Press, 1997; Howard Markel and Stephen Boyle, "The Epidemic Scorecard," The New York Times, April 30, 2003; Rick Weiss, "War on Disease," National Geographic, Feb. 1, 2002; Robert Glass, "AIDS Is Becoming a Global Health Problem," Associated Press, Dec. 17, 1983; "World War II Hepatitis Outbreak Was Biggest in History," Associated Press, April 16, 1987; Gary Gernhart, "A Forgotten Enemy: PHS's Fight Against the 1918 Influenza Pandemic," Public Health Reports, U.S. Government Printing Office, Nov. 1, 1999.


Kelly Whalen is a writer and documentary producer based in Oakland, California.