The transcontinental railroad's construction touched the lives of hundreds of thousands of people. Some desired it, some built it, and some did everything in their power to stop it. Browse a photo gallery of settlers, Native Americans, and workers whose lives were affected by the railroad as it traversed the West.
Three years before the Gold Rush, 87 pioneers took a shortcut westward to California, only to get caught in the snows of the Sierra Nevada.
The unusual life of David Vetter, who lived permanently inside a germ-free environment due to severe combined immunodeficiency.
Begun during the Civil War, the transcontinental railroad employed 20,000 men, mostly immigrants, who built the iron road with their bare hands.
The effort of pioneering researchers to conceive babies through in vitro fertilization.
The New Deal program CCC put three million young men to work in camps across America.
Accounting for America's most famous inventor and his role in America's future.
In the early 1830s, Texas, ruled by Mexico, held 20,000 U.S. settlers and 4,000 Mexican Tejanos, forcing residents to pick sides.
Native Alaskans, oil company representatives, environmentalists, politicians, and others tell the story of the 800-mile pipeline.