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WATCH: Pelosi, Ryan say Conyers should resign from Congress

DETROIT — The top Democrat in the U.S. House says Michigan Rep. John Conyers should resign in the face of allegations of sexual misconduct. Shortly after, House Speaker Paul Ryan made the same call for Conyers’ resignation.

Minority Leader Nancy Pelosi told reporters Thursday that the accusations against Conyers are “serious, disappointing and very credible. It’s very sad.” Ryan, citing the “torrent” of allegations against Conyers, said the congressman should resign immediately.

During his weekly news briefing, House Speaker Paul Ryan said Conyers “should resign immediately.”

Conyers is the longest serving member of the House. He has faced increasing calls from House Democrats for him to step down as several former aides have come forward to accuse him of inappropriate sexual behavior.

On Wednesday, Conyers’ Detroit-area attorney Arnold Reed told the AP that Conyers is innocent and has no plans to step down. Conyers was hospitalized in Detroit on Thursday.

Pelosi told reporters “zero tolerance means consequences – for everyone no matter how great the legacy it’s not licensed to harass or discriminate. In fact it makes it even more disappointing.”

WATCH: The politics of sexual harassment revelations