At 22, William Lloyd Garrison moved to Boston and settled on the abolition of slavery as the cause that would give meaning to his life.
John Brown put little stock in abolition through peaceful means. In 1855, he headed to the slave state of Kansas.
The Fugitive Slave Law of 1850 made the hunting down of escaped slaves, even in free states, fully legal.
After having escaped to New York, Frederick Douglass and his wife Anna moved to New Bedford, Massachusetts.