The Amezcua-Contreras brothers operating out of Guadalajara, Mexico
head up a methamphetamine production and trafficking organization with
global dimensions. Directed by Jesus Amezcua, and supported by his
brothers, Adan and Luis, the Amezcua drug trafficking organization today
is probably the world's largest smuggler of ephedrine and clandestine
producer of methamphetamine. With a growing methamphetamine abuse
problem in the United States, this organization's activities impact on a
number of the major population centers in the U.S. The Amezcua
organization obtains large quantities of the precursor ephedrine, utilizing
contacts in Thailand and India, which they supply to methamphetamine
labs in Mexico and the United States. This organization has placed trusted
associates in the United States to move ephedrine to Mexican
methamphetamine traffickers operating in the U.S. Jose Osorio-Cabrera, a
fugitive from a Los Angeles investigation until his arrest in Bangkok, was
a major ephedrine purchaser for the Amezcua organization.