Nancy S. Wexler, who is widely known for her scientific contributions toward a cure for Huntington's disease, is professor of neuropsychology at Columbia University and president of the Hereditary Disease Foundation. Dr. Wexler has led a twenty-year study focusing on the world's largest family with Huntington's disease, which led to the discovery of a gene associated with the disease at the tip of human chromosome 4. One result of her work was the development of a presymptomatic test for Huntington's disease that can determine who is carrying the fatal gene prior to the onset of symptoms. From 1989 to 1995, Dr. Wexler, who holds her Ph.D. in clinical psychology from the University of Michigan, served as chair of the Joint NIH/DOE Ethical, Legal and Social Issues Working Group of the National Center for Human Genome Research.