Trump routs final GOP rivals but some Republicans refuse to fall in line

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• HARI SREENIVASAN:

  The Republican presidential race is effectively over as of tonight, and the party's new leader is looking ahead. At the same time, detractors now face a decision: how to reconcile with the new reality.

  John Yang has our report.

• JOHN YANG:

  On his first day as the apparent Republican nominee, Donald Trump said he's confident the party will fall in behind him, but that some were welcome to leave.

  DONALD TRUMP (R), Republican Presidential Candidate: I don't think it's imperative that the entire party come together. I don't want everybody. I don't even want certain people that were extraordinarily nasty. Let them go their own way.

• JOHN YANG:

  Trump, who rails against politics as usual, said he's looking for a running mate with a political background to help him navigate Washington.

  It took just a little more than 300 days for the outsider to demolish a field of 16 rivals, including current and former officeholders with more than a century of combined government experience.

  Late today, the last opponent standing, Ohio Governor John Kasich, made it official.

  GOV. JOHN KASICH (R-OH), Republican Presidential Candidate: As I suspend my campaign today, I have renewed faith, deeper faith that the lord will show me the way forward and fulfill the purpose of my life.

• JOHN YANG:

  Ted Cruz quit last night after Trump routed him in the Indiana primary.

  SEN. TED CRUZ (R-TX), Republican Presidential Candidate: We gave it everything we have got, but the voters chose another path.

• JOHN YANG:

  Party chairman Reince Priebus said it's time for the party to get behind Trump and start working toward November.

• REINCE PRIEBUS, Republican National Committee Chairman:

  We have got to unify. We need time to unify. And — and we will unify. But this is what today starts, which is this unification process.

• JOHN YANG:

  But a parade of prominent Republicans is heading for the exits, some even burning their voter registration cards.

  Freshman Senator Ben Sasse of Nebraska said he could never vote for Trump, tweeting last night: "Reporters keep asking if Indiana changes anything for me. The answer is simple. No."

  And one-time Trump rival senator Lindsey Graham tweeted, "If we nominate Trump we will get destroyed, and we will deserve it."

  Despite losing Indiana, Democratic front-runner Hillary Clinton now claims 93 percent of the delegates needed to clinch her party's nomination. But Bernie Sanders made clear last night he's not going anywhere.

  SEN. BERNIE SANDERS (VT-I), Democratic Presidential Candidate: I understand that Secretary Clinton thinks that this campaign is over. I have got some bad news for her.

  (CHEERING AND APPLAUSE)

• JOHN YANG:

  Clinton, meanwhile, turned her attention to Trump, as she did today on CNN.

  HILLARY CLINTON (D), Democratic Presidential Candidate: I have seen the presidency up close from two different perspectives, and I think I know what it takes. And I don't think we can take a risk on a loose cannon like Donald Trump running our country.

• JOHN YANG:

  Already launching a general election campaign, while still working to secure her own nomination.

  For the "PBS NewsHour," I'm John Yang.

• HARI SREENIVASAN:

  We will explore the new lay of the land on both sides of the presidential race after the news summary.