WATCH: South African President Cyril Ramaphosa delivers remarks on COVID-19 vaccine inequality across Africa

The inequity of COVID-19 vaccine distribution came into sharper focus Thursday as many of the African countries whose populations have little to no access to the life-saving shots stepped to the podium to speak at the U.N.’s annual meeting of world leaders.

Watch Ramaphosa’s remarks in the player above.

Already, the struggle to contain the coronavirus pandemic has featured prominently in leaders’ speeches over the past few days — many of them delivered remotely exactly because of the virus. Country after country acknowledged the wide disparity in accessing the vaccine, painting a picture so bleak that a solution has at times seemed impossibly out of reach.

South Africa’s president Cyril Ramaphosa pointed to vaccines as “the greatest defense that humanity has against the ravages of this pandemic.”

READ MORE: For countries with few vaccine doses, fighting COVID-19 is ‘a race from behind’

“It is therefore a great concern that the global community has not sustained the principles of solidarity and cooperation in securing equitable access to COVID-19 vaccines,” he said. “It is an indictment on humanity that more than 82% of the world’s vaccine doses have been acquired by wealthy countries, while less than 1% has gone to low-income countries.”

He and others urged U.N. member states to support a proposal to temporarily waive certain intellectual property rights established by the World Trade Organization to allow more countries, particularly low- and middle-income countries, to produce COVID-19 vaccines.

Angola president João Lourenço said it was “shocking to see the disparity between some nations and others with respect to availability of vaccines.”

“These disparities allow for third doses to be given, in some cases, while, in other cases, as in Africa, the vast majority of the population has not even received the first dose,” Lourenço said.

The U.S., Britain, France, Germany and Israel are among the countries that have begun administering boosters or announced plans to do so.

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Benido Impouma, a program director with the World Health Organization’s Africa program, noted during a weekly video news conference that the surge in new COVID-19 cases is starting to ease in Africa “but with 108,000 new cases, more than 3,000 lives lost in the past week and 16 countries still in resurgence, this fight is far from over.”

“Fresh increases in cases should be expected in the coming months,” Impouma said. “Without widespread vaccination and other public and social measures, the continent’s fourth wave is likely to be the worst, the most brutal yet.”

On Wednesday, during a global vaccination summit convened virtually on the sidelines of the General Assembly, President Joe Biden announced that the United States would double its purchase of Pfizer’s COVID-19 shots to share with the world to 1 billion doses, with the goal of vaccinating 70% of the global population within the next year.

The move comes as world leaders, aid groups and global health organizations have growing increasingly vocal about the slow pace of global vaccinations and the inequity of access to shots between residents of wealthier and poorer nations.

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The World Health Organization says only 15% of promised donations of vaccines — from rich countries that have access to large quantities of them — have been delivered. The U.N. health agency has said it wants countries to fulfill their dose-sharing pledges “immediately” and make shots available for programs that benefit poor countries and Africa in particular.

Biden, earlier this year, broke with European allies to embrace waivers to intellectual property rights for the vaccines, but there was no movement Wednesday toward the necessary global consensus on the issue required under World Trade Organization rules.

While some nongovernmental organizations have called those waivers vital to boosting global production of the shots, U.S. officials concede it is not the most constricting factor in the inequitable vaccine distribution — and some privately doubt the waivers for the highly complex shots would lead to enhanced production.

Associated Press writers Carley Petesch in Dakar, Senegal, Zeke Miller in Washington and Jennifer Peltz at the United Nations contributed to this report.

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