CRISPR

First CRISPR treatment for sickle cell, other blood disease shows early benefits in two patients

By Sharon Begley, Adam Feuerstein, STAT

The first two patients to receive a CRISPR-based treatment for the inherited blood disorders sickle cell disease and beta thalassemia have benefited from the experimental therapy and experienced only temporary and treatable side effects.

Doctors use CRISPR gene editing against cancer for the 1st time in the U.S.

By Marilynn Marchione, AP Chief Medical Writer

Doctors were able to take immune system cells from the patients' blood and alter them genetically to help them recognize and fight cancer, with minimal and manageable side effects.

CRISPR gene-editing ‘eliminates’ HIV in some mice. What does it mean for humans?

By Berly McCoy

Antiretroviral therapy is the standard HIV treatment, but patients are never rid of the virus. A new study raises the possibility of HIV elimination through gene-editing with CRISPR.

‘Jumping genes’ could help CRISPR replace disease-causing DNA, study finds

By Sharon Begley, STAT

Researchers describe combining a "jumping gene" with CRISPR enzymes to deliver a a package of DNA to precise addresses in the E. coli genome.

How a snail’s shell gets its twist

By Vicky Stein

Gene-editing with CRISPR reveals why snail shells are asymmetrical and coil either left or right.

NIH director says there’s work to do on regulating genome editing globally

By Lev Facher, STAT

The apparent birth this month of the first genetically modified babies is “a lesson in the potential for human hubris to overtake us,” Dr. Francis Collins, the director of the National Institutes of Health.

CRISPR causes significantly greater DNA damage than previously thought, study finds

By Sharon Begley, STAT

The DNA damage found in the new study included deletions of thousands of DNA bases, including at spots far from the edit. Some of the deletions can silence genes that should be active and activate genes that should be silent,…

This gene editing milestone raises big ethical questions

By PBS News Hour

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U.S. scientists are fixing genetic defects in human embryos. Should you be nervous?

By Nsikan Akpan

For the first time, U.S. scientists have genetically edited human embryos with CRISPR, thanks in part to regulatory loopholes.

CRISPR used to store images and a movie inside living bacteria

By Hyacinth Empinado, STAT

Forget iTunes or your old zipper case of DVDs. How about storing movies in a Petri dish of E. coli? All you need is some genetic engineering with CRISPR.