♪ ♪ ALICE: I think you're a very good match.

You look great together.

♪ ♪ A courier delivered a massive check from Vanth Capital.

She did a noble and generous thing.

I didn't ask her to.

MAYA: She's in love with you!

ALICE: It's kind of life-changing, isn't it, when you just put the self-absorption aside and you focus on the next generation.

You sound like a parent.

ALICE: I'm gonna be.

My insemination's next Wednesday.

You're not alone, Alice.

♪ ♪ ♪ ♪ ♪ ♪ ♪ ♪ (Feldshue chuckles) There.

Now, this is completely painless.

(chuckles): It will only take a few seconds.

You okay?

(chuckles) Question.

Yes.

Could Jack do that?

Well, legally, no.

No, I'm sorry.

Oh, it's all right.

But he can put his hand on, on top of mine.

If... ALICE: Mmm.

How do you feel about that, Jack?

So, we'd be hold, we'd be holding hands?

FELDSHUE: Yeah, just on top.

For this bit?

No, not for this bit, no.

No, for the next bit.

Yeah, okay.

Yeah, that'll be, yeah, that'll be-- yeah.

Absolutely, yeah.

No problem, yeah.

Thanks.

Right.

Question.

Yes.

Could Jack and I have a moment alone?

Oh, well, of course.

Yeah, no, that's, I'll just...

Pop out.

Thanks.

You okay?

Thank you.

(table moving rhythmically) (typing) (table rattling) (rattling, movement continue) (sound stops) Scone?

Okay, wow.

(giggles) (Jack exhales) Not exactly how I expected the day going.

(chuckles): No.

(whispering): Do you think anybody's ever done that in here before?

Oh, God, I hope not.

(both chuckle) Do you think we should, um... Yeah.

Yeah, they probably have another appointment.

Yeah-- God, what a colossal waste of money.

We could have gone to (muted) Borneo.

(laughing) Shh.

(sighs) (whispering): Be careful.

(laughs) (Alice sighs) Bye, now.

JACK: Thanks very much.

Fingers crossed.

Lovely to meet you.

♪ ♪ JACK: Here we go.

(water running) Caffeine-free, obviously, plus a little something to keep your glucose up.

Thank you, but can you please calm down?

(grunts): If it is a pregnancy, definitionally, it's a high-risk one, so... Those definitions are ageist.

So's life-- works both ways.

My little guys need all the help they can get, too.

Your poor old-man sperm.

Struggling to navigate upstream.

(chuckles) Yeah, all right.

Is there anything else?

No, thank you very much, and please go home.

And I'll call you in 12 to 14 days with the results.

I'll also call you, like, 50 times between now and then.

I'm happy to stay.

I'm sure the couch is comfortable?

Do you like fussing over me?

Course I do.

If I was laid up, you'd wait on me hand and foot.

No, I wouldn't.

But I would hire someone.

And I'd be there, also.

That's close enough.

Just think of me like any other possibly pregnant lady.

Not a chance.

(chuckles) Jack?

Yeah.

Do you want to talk about what happened today?

No.

Okay.

Bye!

(calling): Jack?

Yeah.

Actually, can you stay on the couch?

Yeah.

Thank you!

♪ ♪ (blows through lips) ♪ ♪ (people talking in background) (phone vibrating) I didn't hear from you yesterday.

JACK (on phone): I know-- I'm sorry.

I was worried it had gone south or something.

Yeah, no, it, uh, it was...

It went oddly.

It took, yeah, it took an interesting turn.

Well, now you're gonna have to say.

(exhales) Alice and I made love on the insemination table.

RACHEL (laughing): Okey-dokey.

Um, golly.

Hmm, yeah, I know.

Yeah, I, uh, I don't really know how it happened, or what it means, or if it even really means anything.

It, it could have been a one-off.

A valedictory.

Or maybe we crossed a Rubicon again.

Or maybe we crossed it only for a few minutes, and now we'll cross back again.

Or maybe...

So... You're not sure.

(exhales) Not sure, yeah.

But a non-clean slate just got non-cleaner.

So, I wonder if maybe we're... (call ends) (inhales sharply) (exhales) (phone ringing) (phone calling out) (call connects) JACK (over phone): Hello!

Are you all right?

(laughing) So funny.

Your guys can swim.

(screaming and whooping) Whoo, Alice!

Comhghairdeachas!

Comhghairdeachas!

Comhghairdeachas, comhghairdeachas!

What are you saying?

That's Irish for congratulations.

ALICE: Jesus, that takes so long to say.

I know!

I know!

(laughing) Jack?

What?

I think, um...

I think I'm getting good at it.

You're good at what?

Like, real life.

If that's something that you're interested in, or anything that you want to take a risk over.

Oh.

Can we think about it?

When have we ever not thought about it?

Never.

(door intercom buzzes) My food's here, I've got to...

I, I love you.

♪ ♪ (exhales) ♪ ♪ (whoops loudly) How are you feeling, love?

I'm feeling very well, thank you.

(chuckles) Am I right in thinking the baby's, like, the size of a fig?

That's right, yeah.

Next week, a lime.

(chuckles) So...

So we did the standard ten-week workup.

And I need to tell you that it showed some genetic abnormalities that could be indicative of an illness.

What kind of illness?

They could be indicative of cancer.

But then, I mean, cancer?

(quietly): Yeah.

Yeah.

How can they check that when the baby's so small?

It's not the baby.

No.

It's not the baby.

It's you.

♪ ♪ ♪ ♪ JACK: Hi, everybody-- thanks for being here.

Okay, this is stage four bile duct cancer with distant metastases.

The five-year survival rate is two percent.

Conventional therapy is already underway at the point of attack, but there are so many... (clears throat): Sorry, there are so many points of attack that I believe the only way to save this patient's life is to harness her own immune system.

Luckily, we have some experience in that area.

Uh, in related areas.

Okay, this is CTLA-4.

It switches off our T cells after they've killed an infection, but before they start attacking healthy tissue.

Without CTLA-4, our bodies would basically murder themselves.

Cancer cells are clever (muted).

They use CTLA-4 to fool our immune system into thinking everything's okay, and then the cancer cells take over.

So, what we are looking for is a substance that stops our T cells from being fooled, a tumor-specific form of anti-CTLA-4.

PAUL: Even if your theory is right and the formulation exists, and somehow we find it, we'd still have to work out how to deliver it, and then put it through trials, and then get it approved.

Someone'll do it someday.

Yes, maybe, if they've spent a lifetime in cancer research.

You don't just swoop in and cure the worst disease in human history... You don't if you don't try.

We did something similar on Hashimoto's.

We knew where to look on Hashimoto's.

And we got very lucky.

On this, we're in a (muted) rowing boat on an open ocean looking for a drop of water with... We've got lightning-fast computers now.

They can process literally hundreds of candidates a second.

You're not being rational.

You're tilting at windmills, mate.

I've never known what that means.

That this is not gonna work.

And you're taking people and machines away from dengue fever and half a dozen other projects we're this close on!

What are you telling me to do?

Are you telling me to let her go?

I'm telling you to let the doctors do what they do.

They'll fail, Paul.

Their science is old.

Blast away with chemicals and radiation and hope for the best.

Meanwhile, the person suffers and withers in front of you and almost always dies anyway.

That can't happen to Alice.

If there's anything that I can do, I'm gonna do it.

And what if there isn't?

Then I'll die trying, okay?

I'll die trying.

Look it's not that I don't understand.

I'm sure I'd feel the same way if, God forbid, it were Donna.

If this was Donna, we wouldn't even be talking about it because I would've been in from the start.

Okay.

(brakes squeak) Okay?

Okay.

Good man.

I'll start the moment I get back upstairs.

Good man.

Just don't get your hopes up in that way that you do.

This is still insane.

I have to have hope.

Okay, well, hope, just don't believe.

I have to believe.

♪ ♪ (siren blaring in background) (gasps, laughs) JACK: Hello, miss, can I walk you home?

Yeah, you certainly can.

You shouldn't have done this in the middle of a workday.

Ah, I'd spend every minute with you, if you'd let me.

Oh, that's creepy.

Yeah.

How'd it go in there?

You know.

We're all terminal, I'm just a little more terminal than most.

Okay, I, um, called around about your doctors, and they all check out, but people seem especially keen on Dr. Anthony Cedarbaum, because, apparently, he rolls with the punches and he's a student of the game.

So, that's good.

How are you?

I'm, I'm fine.

Mm-hmm?

Yeah.

Yeah, when was the last time you slept?

Can we please not worry about me right now?

Why not?

It's a (muted) excellent change of pace.

Okay, the other thing, all the (muted) online.

Do not Google late at night, but if you do Google late at night, as I admit maybe I was doing recently, don't get caught up in stupid (muted) papers written by, written by stupid people with these ridiculous axes to grind.

It's a waste of time, and it will drive mad, so... (exhales) Jack.

Yeah.

You want to go somewhere?

Sure, yeah, where do you want to go?

You know where.

Cuba?

Our roof.

It's a long trip for you, Alice.

Yeah.

Yeah, of course, I'll set it up.

(chuckles) ♪ ♪ ♪ ♪ (phone ringing) (button clicks) Hey.

I've been, yeah, sorry, I've been waiting for you to...

I was just gonna say that my instinct is, it's got to be a protein, right?

PAUL (on phone): Mine, too, because the monoclonal antibodies are proteins.

Yeah-- yeah, yeah, so that's the place to start, then.

PAUL: Okay.

(Jack gasps) (panting softly): That's got to be the place to start, right?

Are you okay?

(gasping lightly) Yeah, sorry, traffic is, um... (gasping, breath trembling) Uh, I'll, I'll call you back.

Just, you, you keep, you keep doing what you're doing, yeah?

(breath trembling, phone calling out) LYNN (on phone): Jack?

(panting): Hey, uh, Lynn.

(breathes deeply) Thanks for letting me ruin your week.

Yeah, well... We circle the wagons, Cyril.

(sighs) (siren blaring in distance) How you feeling?

(sighs): I'm grand.

It's probably just stress.

Yeah, yeah, exact-- I mean, I'm sure we'll see.

Uh, how's Alice?

(sighs): It's weird, Lynn.

I can tell she's, like, resigned herself to the worst already, which I hate, but makes sense.

She's always been one for the odds.

But she's still putting herself through the chemo.

And God knows what else after that.

I just, I just can't work out why.

Well, for you, obviously.

Thanks for asking after her.

Aye, yeah, well, can't go around hating people.

Except for you, of course.

Of course.

You know, if you ever actually met her, I think that you will really like each other.

I mean, let's not go crazy.

(laughing) (chuckles) You know, I'm good and over you, Jack, I can promise you that.

But it doesn't mean I don't love you.

And it doesn't mean I don't want you wandering the Earth making someone else miserable.

(door opens) PELL: Good morning to you, Mr. and Mrs. Caine.

LYNN: Oh, uh, it's, um, Mr. Caine and Ms. Mixon.

We're not married-- well, we were, but, um, we're not anymore.

I'm married to someone else.

Um... (clicks tongue) You have Ehlers-Danlos syndrome, a genetic disorder of the connective tissue, in your case, of this piece right here, where the artery meets your heart.

Okay.

That sounds bad.

That looks bad.

Because it's an aortic aneurysm, which, had it gone undetected, might have led to dissection, which would have led to death.

But now that we know about it, we can keep it from killing you.

Christ-- okay.

Your medical history says that both your parents died of heart attacks.

Mmm, they did.

No, they didn't.

So, what are my odds?

(clicks tongue) Assuming you behave yourself, 100%.

100... 100...

Okay.

As I said, it's a syndrome, not a disease.

You did say that, yeah.

(both laugh) Sorry to laugh, just, that was a lot to, you know...

It's bad news, but it's not, it's not terrible... News.

News.

Yeah.

You see all this?

This is you and me passing into obsolescence.

Ah, we've still got some time left.

Oh, really?

Have you looked in a mirror recently?

'Cause I did, and the ghost of Marie Curie looked back and told me I was (muted).

Each of these servers is looking at a different set of combinations and permutations.

Normal proteins, novel proteins, synthetic proteins-- a smorgasbord of proteins.

As you can see I chose yellow for failure, just for nostalgia's sake.

All we need is one that turns red.

Essentially, that's it.

The programs are up and running.

All that remains for the humans to do is sit, stare at the screen, contemplating their technological unemployment.

And maybe shout if anything good happens.

And not even that, really, because about 85 alerts will just go off.

So, you may as well just go home and recuperate.

Mm.

I don't like the word "aneurysm."

Alice wants to go on a trip.

So, go on a trip.

That's a good idea-- I'll keep you updated.

I feel like I should be here.

Again, that's ego and neurosis.

She thinks it's gonna be her last one.

You haven't told her, have you?

About the Ehlers-Danlos?

No, not yet-- I will.

No, about this, Jack.

About everything we're doing here.

If it works, she'll be my first phone call, believe me.

And what if...

If it...

If it doesn't, and I told her, then I will spend the rest of my life wishing that I hadn't.

Okay?

Yeah.

Okay.

(luggage wheels rolling) MAYA: Right, so, the Paris leg will be a piece of gâteau, obviously.

(chuckles) Um, and on the layover, an agent named Capucine or Capucina-- I got tired of asking her-- she'll be there to take you to the fancy person's section of the lounge.

And on the second leg, the long leg, all your meals have been pre-loaded.

And I checked, of the 100 or so in-flight films, at least seven aren't based on comic books.

Mmm.

All your documents are in your bag in the order you'll be needing them.

Don't get clever at immigration, because you might wind up in the slammer, and then there's nothing I can do.

Um, at the hotel, tip like a sailor, bottled water only, and the internet is still 3G.

So, yep, no public swearing.

(laughs) Thank you.

You didn't need to do all of that.

It's just muscle memory.

Well, I love you.

What?

I said I'm not paying you.

(chuckles) (suitcase thuds) Out of me way.

(laughs) All yours-- move over.

You all right?

(laughs, clears throat) Yeah?

Okay.

(grunts) Jesus.

(laughs) ♪ ♪ What's wrong?

Nothing.

I don't like leaving Paul in the lurch.

Makes me anxious.

Honestly, I don't feel anxious about anything right now.

Really?

What's that like?

It's good.

(car bumps) DRIVER: Oh, for (muted) sake!

What about now?

Are you anxious now?

No.

Do you think he's hurt?

He didn't even spill his coffee.

Well, then, what's taking so long?

What are they talking about?

(car horn honking) Come on, lads.

Someone's not in holiday mode.

Because we're not yet on holiday.

We're watching these two fellas have a chat.

(exhales): Christ.

This is... Oh, man, this is not good.

You're looking at traffic.

It looks like my phone is bleeding.

It says if we leave now, we get to Heathrow in April.

(sighs, moaning) Jack, if we miss the flight, we'll just get the next flight.

There's... No.

There's, like, the next one's in two days.

(sighs) (people talking in background) I just want to be with you.

(horns honking in distance, people talking in background) You know, I just want to be with you, too.

Good.

Why don't I ask the driver to take our luggage back to my apartment?

I don't understand.

What do we, what do we do?

Whatever we want.

(horns honking in distance, people talking in background) (chuckles) Yeah.

Okay?

Yeah.

ALICE (chuckling): So, how are your tension levels?

JACK: Was a nine.

Now a seven.

Ooh, great.

(chuckles) Seven-and-a-half.

(laughs) Oh, my goodness, do you know what's on this street?

What?

My favorite house.

Where?

It's there, it's that white one, with those windows.

Oh.

Beautiful, yeah.

Not your usual taste, though, I wouldn't have thought.

I don't know.

I feel like I would've been ready for something different, you know?

Yeah.

Something warmer.

I would've liked to have tried to have kids again.

With you.

Yeah.

Wouldn't have wanted to raise them in my refrigerator of an apartment, though.

I like your flat.

(chuckles) Yeah, there's a time in life for everything, isn't there?

But I feel like a kid needs a...

Window in the bathroom.

That's fair enough.

(quietly): Yeah.

I can see us, though.

Two kids.

Them windows.

(both chuckle) Can you?

Boys or girls?

Either.

Well, one of each, if I could choose.

(chuckles) Agreed.

Celia would have siblings.

Yeah.

The Caine-Long kids, I mean... (laughing): Yeah.

Polite, charming, more than usually funny.

Nice.

Oh, my God, do you want a fizzy drink?

Do you?

(muted) yeah, I want a fizzy drink.

Might be my last one.

My farewell fizzy drink.

I'll buy you one.

I'll buy you one.

No, I'll buy you one.

Let me buy you one.

No, I'll buy you one.

Alice, come on, Jesus (muted).

(laughs) I'll buy you one.

No, I'll get it.

No, it's okay.

I just want to...

Please, don't do this.

(laughs) Hello.

Hi.

I'm gonna...

I'd like two fizzy drinks.

I'm about to pay for two fizzy drinks, please.

Two fizzy drinks.

♪ ♪ JACK: Mm-hmm.

ALICE: When the kids are old enough for us not to go totally bananas and lose our minds, we take them on holiday.

Where do we go?

Skiing.

No.

I've only been skiing once.

I nearly killed myself and a bunch of other people.

(laughs) It's not funny.

I think I need a, a friction-based relationship between myself and the Earth's surface.

I need that with people.

I know exactly what you mean.

I'm aware.

(chuckles) Um...

Okay, no skiing, but we'll go somewhere.

Mm-hmm.

We'll travel somewhere where... (in accent): America.

No!

(muted) America?

Donegal!

We certainly can.

I've never been.

Yeah.

Amazing beaches, amazing people, amazing coastline, amazing fiddle music.

It's amazing.

Oh!

And if you know where to go, there's nobody else around.

Apart from sheep and a few goats.

Okay, and on day one, the kids learn to not, to stay away from the goats.

Mm.

You make friends, but at a distance.

Yeah.

They'll be good at that if it's hereditary.

(muted) stop.

It's so, it's true.

(laughs) And so what are we doing?

While the kids are avoiding goats?

(inhales deeply) We're gamboling.

You what?

Gambling?

No, we're gamboling.

Gam-bol-ing.

Gamboling!

Yeah.

Gamboling.

Right?

Show me a gambol.

I'll do a gambol if you do a gambol.

All right.

Yeah?

Mm-hmm.

Okay.

Finished with your fizzy drink?

ALICE: What in the actual (muted)?

(both laugh) JACK: You do it, then, go on.

No, I'll do you gamboling.

Don't do me gamboling, you do you gamboling.

Yeah, whew!

Okay, this is you gamboling.

That's... Ooh, I'm just gamboling!

Like... Don't do the accent, all right?

(laughs) You do you gamboling, then.

I would just, I would just gambol, you know?

Like, cool.

But that's not gamboling!

You gotta put some spirit into it.

ALICE: I never go back to finance.

JACK: What do you do?

ALICE: Charge ahead with philanthropy, trying bit by bit to erase the moral stain of wealth.

(Jack chuckles) ALICE: You?

I'm a lab rat till the day I die.

You'll have to drag me out by my ankles.

(laughs): I'd like to see that.

And then we see just little enough of each other that when we do, it's, you know...

It's still thrilling.

It's always thrilling, Alice.

People say at some point the excitement fades away, but, with you, it never has.

I feel like that about skiing.

And you-- I should have led with that.

Yeah.

(laughs) Maybe my mistake with skiing was the same as my mistake with you.

I never learned to slow down.

♪ ♪ Mm.

Well, I wouldn't want to be one of those couples who sits in silence, having run out of things to say 25 bloody years ago.

That's like a living death, isn't it?

Which is arguably worse than a dying death.

Maybe they're just content.

I don't trust content, you know.

Isn't content, like, the younger cousin of bored (muted)less?

No!

No?

What about when we're older?

Like when we're 70?

Or 80, 90?

Oh, well, when we're 70, 80, or 90, we begin, in a very entertaining way, to totally lose our wits.

Mm-hmm, chaos.

Absolute chaos.

(both laugh) How's your tension level?

When I'm 90, I hope it's zero.

I hope.

(laughs) ALICE: Do you know where we are now?

JACK: Yeah.

We're a couple of streets from Celia's school.

Which you know because you've snuck over there once or twice?

Which I do know because I might have snuck over there once or twice.

Imagine her when we're 90.

Oh, my God, she'll have had a dance career.

(chuckles) And she'll have been all over the world.

(laughing): And she'll be a diplomat.

A diplomat?

I think she'd be really good at it.

Oh, 'cause she's had the training.

Right, yeah.

I blame myself for that.

I blame me.

She's been well-loved, though.

Mm.

And there's definitely worse things than that.

Yes, there are.

(laughing softly): Oh, my God!

JACK: Oh, my God.

What's she... What's she doing?

Well, she's meeting a boy, Jack.

She didn't tell me about that.

You think?

(talking softly, laughing) Do you think she'll be happy?

(softly): Yeah.

Do you think she'll see less trouble than we did?

Yeah.

(kids continue talking) Maybe I should just nip over and say hello.

No!

Unless you want to be reviled for the rest of time.

Why don't you, why don't you go over and say hello?

She loves you.

Nice try.

She doesn't want to see me, either, Jack.

(chuckles) JACK: Can we go and get a proper drink?

ALICE: Oh, yeah.

Can we get five?

(chuckling): Yes, we can.

Okay.

ALICE: Okay, so we're 100 years old.

(exhales): Well done, us.

(cheers) (both chuckle) And you're fine.

You're like, you're like a field horse, but I'm on the fade.

What do we do?

(inhales sharply) We go for a walk and we have a fizzy drink.

And we do what we did today, but in reverse.

We reminisce.

(people talking in background) And you know how I would feel?

No.

I would feel exactly the same as today, which is that because you're here, it's too soon.

(voice wavering): It's too soon.

(people talking in background) (breathes deeply) Do you think these hipsters are looking at us thinking we've run out of things to say?

If they are, they are morons.

(glasses sliding) Maybe content is okay, eh?

Why are you not angry, Alice?

(breathes deeply) Because I'm apoplectic.

Do you know what I thought when they first gave me my diagnosis?

No.

I thought, "These people are thieves-- they're thieves of time."

But, um...

I don't want to spend the days that I've got left just being angry about the ones that I'm not gonna have.

Jack?

Are you gonna be all right if I'm not one of these, you know, two-percenters?

No.

Are you?

Jack, I'm gonna be dead.

I think-- technically, I think dead's the opposite of all right.

Yeah, yeah, sorry.

(both laughing) (inhales deeply) Can I tell you a secret now?

Whatever happens, I think we're gonna see each other again.

You think so?

Mm-hmm.

Do you think I'm absolutely crackers for believing that?

No.

You don't think it's, like, the desperate delusions of a... Nearly expired human?

No.

Do you remember that first night that we met?

(laughing): I do remember the first time we met, yeah.

Do you remember what I asked you?

Yeah, you asked me (muted) everything.

You asked me everything, all in a row, like this.

(laughs) Do you remember when I asked you if you were religious?

Mm-hmm.

I asked you back, and you never answered.

So, are you religious now?

No!

May, I mean... Maybe-- I don't know.

I mean, it's hard to find proof, isn't it?

(chuckles) Mm.

(sighs) But I think there are hints.

You're saying you've had a hint?

I am saying that, yeah.

And what was the hint?

(softly): I'm looking at him.

(phone ringing) That's Paul's ring.

(chuckles) Just take, take-- go on, take it.

Do you want the same again?

Oh, yeah, please.

Yeah, thanks.

(phone ringing and vibrating) Paul.

PAUL: Oh, it's you.

I thought you'd be on a plane.

I, I was expecting to leave a message.

No-- do you, uh... Do you have news?

No, mate, I'm sorry, I...

I was just calling to tell you we're through the first 100 million candidates.

I was just keeping you apprised.

I'm sorry.

It's all right.

But, look, 100 million down, but billions to go.

So, this is only the first of approximately 17,000 phone calls.

She wouldn't want this, Paul.

What?

And it's not gonna work, is it?

We should spend her time more wisely.

(sighs): Stop it.

Go back to the other projects.

Stand down.

Are you sure?

Yeah.

Okay.

Okay.

♪ ♪ (people talking in background) ♪ ♪ ♪ ♪ Just in time.

(exhales) Thank you.

♪ ♪ To us.

Mm.

(glasses clink) ♪ ♪ See, I wondered how this would all happen.

ALICE: But it's not like, you know, real life-- it's like fantasy.

I mean, it's not like this is ever gonna end, is it?

I hadn't realized that.

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