>>> COMING UP NEXT ON ARIZONA HORIZON: >> WE'LL HEAR ABOUT HOW AND WHY ARIZONA'S BECOME A MAJOR HUB FOR SEMI-CONDUCTOR MANUFACTURING.

ALSO TONIGHT, A LOOK AT POTENTIAL NEW TREATMENT FOR LEWY-BODY DEMENTION, THE 2ND-MOST COMMON NEURO-DEGENERATIVE DISEASE AFTER ALZHEIMER'S.AND, A NEW DOCUMENTARY LOOKS AT THE REALITIES OF GROWING UP POOR IN AMERICA.

THOSE STORIES AND MORE, NEXT, ON ARIZONA HORIZON.

>>GOOD EVENING AND WELCOME TO ARIZONA HORIZON.

I'M TED SIMONS.

CONGRESS-WOMAN ELECT ADELITA GRIJALVA AND FELLOW ARIZONA DEMOCRATS AGAIN TODAY CALLED ON THE REPUBLICAN SPEAKER OF THE HOUSE TO SWEAR GRIJALVA INTO OFFICE AFTER HER ELECTION TO ARIZONA'S 7TH CONGRESSIONAL DISTRICT.

>> LET'S BE CLEAR.

I'LL BE THE 218th SIGNATURE ON THE EPSTEIN FILES.

HE'S DOING EVERYTHING TO SHIELD FROM ACCOUNTABILITY.

THAT'S NOT LEADERSHIP BUT OBSTRUCTION.

EVERYDAY I'M NOT SWORN IN IS ANOTHER DAY MY CONSPEECHENTS ARE BLOCKED FROM SERVICES AND EXCLUDED FROM DEBATES THAT EFFECT THEIR LIVES.

>> SENATOR MARK KELLY JOINED TODAY'S PRESS CONFERENCE OUTSIDE THE U.S.

CAPITOL.

>> THIS IS WRONG.

THE SPEAKER IS DOING THIS FOR POLITICAL REASONS.

HE DOESN'T LIKE LOSING THE ONE SEAT MAJORITY.

IT'S SPECIFIC.

>> KELLY'S FELLOW U.S.

SENATOR, RUBEN GALLEGO, "DID" GO BEYOND THAT IN "HIS" THOUGHTS AS TO "WHY" THE SPEAKER IS HOLDING THINGS UP.

SPEAKER JOHNSON IS TRYING TO COVER UP FOR PEDOPHILES.

>> SPEAKER JOHNSON IS PROTECTING PEDOPHILES.

HE WANTS TO PROTECT THOSE FILES AND ALL OF THOSE PEDOPHILES THAT WILL BE REVEALED.

HE HAS ONE MORE DAY TO PROTECT THE PEDOPHILES.

WHETHER IT'S INVOLVING DONALD TRUMP OR HIS RICH ELITE FRIENDS.

THAT'S WHAT THE SPEAKER IS DOING HERE.

IT'S CHANGED FROM DAY ONE, DAY TWO, OR DAY THREE.

HE'S TRYING TO COVER UP FOR THE PEDOPHILES.

>> BUT THE SPEAKER CONTINUES TO DEFEND HIS ACTIONS IN "NOT" ADMINISTERING THE OATH TO GRIJALVA.

>> I'M HAPPY TO ADMINISTER TO HER AS EVERY OTHER MEMBER.

IT'S A GREAT HONOR.

SHE WON AFTER THE HOUSE WAS OUT OF SESSION.

WE HAVEN'T HAD A FULL SESSION.

SHE DESERVES A FULL HOUSE WITH MEMBERS AND HAVE HER FAMILY AND FRIENDS.

THAT'S NOT BEEN SCHEDULED BECAUSE WE HAVE.

HAD THE SESSION YET.

>> JOHNSON BLAMES THE GOVERNMENT SHUTDOWN FOR CONGRESS REMAINING OUT OF SESSION.

>> SEMI-CON WEST IS ONE OF THE MICRE- ELECTRONIC INDUSTRY'S BIGGEST CONFERENCES AND FOR THE PAST 50- YEARS THE EVENT'S BEEN HELD IN THE BAY AREA.

BUT NOT THIS YEAR.

THIS YEAR SEMI-CON WEST WAS HELD RIGHT HERE IN PHOENIX, AN INDICATION OF THE VALLEY'S POSITION IN THE WORLD OF MICRO-ELECTRONICS.JO INING US NOW IS DANNY SEIDEN, PRESIDENT AND CEO OF THE ARIZONA CHAMBER OF COMMERCE AND INDUSTRY.

GOOD TO SEE YOU AGAIN.

>> THANK YOU FOR HAVING ME ON.

>> YOU MUST HAVE BEEN ALL OVER THE PLACE.

>> IT WAS A WATERSHED MOMENT FOR ARIZONA.

IT'S BEEN IN SAN FRANCISCO.

IT USED TO BE THE SILICON VALLEY, THE CENTER OF THE UNIVERSE.

NOT ANY MORE.

IT'S THE ON THE MAP FOR SEMICONDUCTORS.

ALL WEEK LONG, WE HAD RECORD ATTENDANCE.

THOUSANDS CAME TO SEE WHAT WE HAVE TO OFFER.

THIS IS BIOSPHERE OFFERING.

>> LET'S TALK MORE ABOUT WHY WE LEAD THE WAY AND WHY WE ARE A HUB.

WE'LL BE ON A ROTATING BASIS FOR THE CONFERENCE.

>> WE ARE.

I THINK, AFTER, THE FACT OUR ATTENDANCE WAS 64% HIGHER THAN THE LAST IN SAN FRANCISCO.

YOU WILL SAY.

WE SHOULD MOVE EVERYTHING TO ARIZONA FULL-TIME.

I'M NOT AN ADVOCATE FOR ARIZONA BUT I BET THAT'S WHAT THEY WOULD DO BECAUSE WE ARE SMART.

>> I MEAN, WE HAVE DONE STORIES OVER THE YEARS AND SEEN IT GROWTH AND DEVELOPMENT, WHAT'S IT ABOUT?

>> IT'S BEEN DECADES IN THE MOMENT.

IN THE 50s YOU GET INTO INTEL AND ASM AND MORE.

WE HAVE BEEN MAKING SEMICONDUCTORS FOR 70 YEARS.

WE KNOW HOW TO DO IT AND IT'S IN OUR DNA.

IT'S A FOCUS LEGISLATURE OF LEADERSHIP THAT SAID WE NEED THE RIGHT POLICIES.

UP TO 165 MILLION MAKING THE SEMICONDUCTORS IN THE WORLD.

THAT DOESN'T HAPPEN BY ACCIDENT.

SANDRA DESERVES A LOT.

>> OKAY, THE IMPACT OF THE 2022 CHIPS AND SCIENCE ACT.

THAT HAD TO BE A BIG PLAYER.

>> THAT WAS A HUGE ASSIST TO FOREIGN COMPANIES MOVING THEIR FACILITIES FROM SOUTHEAST ASIA INTO THE U.S.

THAT WAS HELPFUL TO COMPANIES LIKE AMCOR.

3,000 JOBS AND MAKING ADVANCED PACKAGING.

>> YOU MENTIONED TSMC.

THE NUMBERS ARE STAGGERING.

THEY ARE HARD TO COMPREHEND WITH THE 65 BILLION HERE AND 6 BILLION THERE.

IS THIS STILL THE PLAN.

>> THEY ARE.

REWITH UM TO TWO.

THEY ANNOUNCED MORE.

TWO ADVANCED PACKAGES.

THERE IS SO MUCH MORE TO COME OUT THERE.

YOU ARE HEARING THE NAMES NOW NVIDIA AND AMD.

THIS IS A GENERATIONAL CHANGE.

IT WILL GO FOR 50 YEARS PLUS BRINGING BILLIONS INTO THE STATE.

>> THAT'S WHY SILICON VALLEY HAD THAT SUCCESS SO LONG.

WHEN THEY WERE THE CENTER THEY HAD THE INNOVATION.

THAT'S MOVING TO ARIZONA AND HAPPENING HERE.

WE HAVE TO TALK ABOUT THE WATER CONCERNS.

WE HAVE A CONCERN OVER WATER.

THEY ARE COMING IN FROM DENMARK AND OVER SEAS.

WHAT DO YOU SAY WHEN THEY ASK WHERE ARE WE LOOKING FOR THE WATER INTEL HAS BEEN DOING THIS FOR 50 YEARS.

THEY JUST ANNOUNCED BUILDING A WATER RECYCLING PLANT TO TREAT THE WASTE WATER AS WELL.

AGAIN, THEY ARE GOOD CORPORATE CITIZENS, AGAIN, IT'S A MODEL FOR THE REST OF THE WORLD.

WE CAN DO THAT AND MAKE IT SUSTAINABLE.

>> DOES ARIZONA HAVE ENOUGH POWER FOR THE PLANTS.

>> NO YOU GET TO THE TOP ISSUE.

WE DO RIGHT NOW, TED.

WE HAVE BEEN SMART AT MANAGING.

THEY HAVE DONE A GOOD JOB.

THE CORPORATION COMMISSION MADE THIS A PRIORITY SAYING WE NEED TO MAKE SURE WE ARE INVESTING THE RIGHT ASIA MOUNT TO BUILD OUT THE CAPITAL INFRASTRUCTURE.

WE NEED TO DUPLICATE WHAT WE HAVE DONE IN THE NEXT FIVE.

IT WILL REQUIRE INVESTMENTS WE ARE THE BEST AT THIS WE KNOW WHAT WE ARE DOING AND SHOULD DO MORE OF IT.

>> CRITICS SAYING, WAIT A MINUTE.

I GUESS THE QUESTION WOULD BE, YES, VERY CONSERVATION MINDED.

THAT'S A GOOD THING.

IT STILL MEANS USING A LOT OF WATER AT A TIME WHEN THE COLORADO RIVER IS IN JEOPARDY.

>> YOU ARE RIGHT.

THEY WILL BE UP SOON.

ARIZONA MADE THE BEST CASE.

THE MORE WATER YOU GIVE US WE PRODUCE MORE VALUE.

NOT JUST THE STATE BUT OUR COUNTRY.

WE NEED THE CHAMPION.

WE HAD THEM IN THE PAST.

WE HAD SENATOR KYLE.

THEY HAD GIANT WATER LOOK FOR OUR SENATORS I'VE TALKED ABOUT THIS ONE FOR A LONG TIME.

>> THE CITY SHOULD BE SO PROUD.

I'LL MAKE THAT PREDICTION.

WORTH BILLIONS OF DOLLARS.

>> I APPRECIATE IT.

DEMENTIA OR LBD IS THE 2ND-MOST COMMON NEURODEGENERATIVE DISEASE AFTER ALZHEIMER'S DISEASE.

BANNER SUN HEALTH RESEARCH INSTITUTE IS WORKING ON A NEW TREATMENT FOR THE DISEASE.

WE LEARNED MORE FROM DR.

PARICHITA CHOUDHURY, COGNITIVE AND BEHAVIORAL NEUROLOGIST WITH BANNER SUN HEALTH RESEARCH INSTITUTE.

>> WE ARE TALKING LOUIE BODY DEMENTIA.

>> THIS IS THE SECOND MOST CAUSE FOR DEMENTIA.

IT'S VERY COMMON, EXCEPT, UNDER DIAGNOSED.

WE DON'T HEAR ABOUT IT.

IT HAS TWO MAJOR CONPONNENTS.

ANOTHER ENTITY CALLED DEMENTIA WITH LOUIE BODIES.

NOT VERY CREATIVE.

>> THEY ARE WHAT?

>> THESE ARE LITTLE INCLUSIONS AND CLUMPS OFF OF A PROTEIN THAT ARE FORMED IN THE.

THEY CAN ONLY BE SEEN UNDER THE MICROSCOPE IN THE BRAIN.

>> THIS HAPPENS BECAUSE OF GENERICS?

ENVIRONMENTAL?

DO WE KNOW HOW?

>> COMBINATION, THERE ARE CERTAIN GENES THAT CAN MAKE YOU HAVE LOUIE BODY DISEASE.

IT'S MOSTLY ENVIRONMENTAL.

>> I ONLY HEARD ABOUT LEWY BODY DEMENTIA BECAUSE OF ROBIN WILLIAMS, WAS IT KNOWN BY ANOTHER NAME IN THE PAST?

>> NO, IT DIDN'T HAVE A DIFFERENT NAME.

YOU ARE RIGHT, IT'S NOT WELL KNOWN UNLESS YOU TALK ABOUT ROBIN WILLIAMS.

PART OF THE REASON, IT'S DIFFICULT TO DIAGNOSE.

IT HAS FUTURES LIKE PARKINSON DISEASE AND ALZHEIMER'S.

THEY ARE SECOND COUSINS OF BOTH DISEASES.

THEY GET MISDIAGNOSED AS ONE OR THE OTHER.

UNLESS PEOPLE HAVE SYMPTOMS OF PARKINSONS THIS DISEASE IS DIFFICULT TO DIAGNOSE.

SECONDLY, WE DON'T HAVE TESTS THAT DIRECTLY SHOW THE PRESENCE OF LEWY BODIES IN THE BRAIN UNTIL RECENTLY.

>> YOU HAVE THEM NOW.

>> THE PROTEINS THAT CAUSE LEWY BODY TO FORM.

WE CAN DETECT THEM IN THE SKIN AND CSF.

>> OKAY, EARLY SIGNS?

>> YOU START OUT WITH COGNITIVE PROBLEMS MEMORY AND THINKING OR MOVEMENT PROBLEMS.

IF YOU START OUT WITH MOVEMENT PROBLEMS AND SEVERAL YEARS LATER DEVELOP DEMENTIA YOU HAVE PARKINSON DISEASE DEMENTIA.

IF YOU START OUT WITH MOVEMENT AND MEMORY PROBLEMS, KIND OF AROUND THE SAME TIME, OR THE MEMORY PROBLEMS FIRST, YOU CAN HAVE DEMENTIA WITH LEWY BODY.

>> ARE THERE AGES AT RISK HERE.

>> MOST COMMONLY IN THEIR 60s AND 70s.

MORE IN THE 70s TEND TO HAVE DEMENTIA WITH LEWY BODIES.

YOU CAN HAVE SOMETHING CALLED REMEMBER SLEEP BEHAVIOR DISORDER.

ACTING OUT YOUR DREAMS.

WE DON'T THINK OF THAT MUCH BUT IT COULD BE OF WHAT'S TO COME.

>> LIKE SLEEPWALKING.

>> TYPICALLY PEOPLE DON'T COMPLETELY GET OUT OF BED BUT MOVE THEIR ARMS OR LEGS.

IF YOU HAVE A BED PARTNER THEY MIGHT GET PUNCHED OR INJURY THEMSELVES AND FALLOUT OF BED AND SO FORTH.

>> OKAY, WE HAVE LEWY BODY DEMENTIA.

HOW DO WE TREAT IT.

THERE ARE SYMPTOMATIC TREATMENTS WE KNOW OF.

WE CAN HAVE THE SAME DRUGS AS ALZHEIMER'S FOR THE COGNITIVE PROBLEMS AND THE NEURO PSYCHIATRIC PROBLEMS THAT COME WITH THE DISEASE.

>> THOSE SLOW THE PROGRESSION.

THEY DON'T NECESSARILY KNOCK IT OUT.

>> THEY HELP STABILIZE FUNCTION AND THEY HELP WITH SYMPTOM MANAGEMENT.

>> WHAT IS NEXT IN THE RESEARCH?

>> WE HAVE BEEN BEHIND ALZHEIMER'S IN THE LEWY BODY WORLD.

WE HAVE MADE PROGRESS IN THE LAST FEW YEARS.

WE HAD A TRIAL THAT COME UP WITH A DRUG THAT ESSENTIALLY, IT'S A PHRASE TWO TRIAL.

YOU LOOK AT SAFETY.

IT'S FOUND TO BE SAFE AND HAD GREAT EFFICACY.

SLOWING DOWN THE DISEASE BY 70 TO 80%.

IT'S VERY PROMISING AND WE HOPE FOR A BIGGER TRIAL.

>> IT SLOWS DOWN FOR NOW BUT IMPOSSIBLE TO FIGURE OUT THE LONG-TERM EFFECTS OF THE DRUG.

>> THAT'S TRUE BUT PRETTY SAFE.

WOE HAVE SOME IDEA OF THE EFFECTS.

>> BEFORE YOU GO BANNER SUN RESEARCH INSTITUTE STARTED AS A TAILOR.

>> APPARENTLY.

IT WAS STARTED BY THE COMMUNITY, YOU KNOW, WANTING TO HAVE PEOPLE STUDY OLDER ADULTS AND AGING.

THERE WAS A CLINIC AN TAILOR IN A PARKING LOT.

>> IT WAS EXPANDED FROM THERE.

BODY DONATION PROGRAM AND CLINICAL TRIAL PORTFOLIO.

WE DO OTHER TYPES OF RESEARCH.

>> SOUNDS LIKE YOU ARE DOING GREAT WORK.

THANK YOU FOR JOINING US AND SHARING THAT INFORMATION.

>> I'M HAPPY TO SHED LIGHT ON IT.

>> THE PBS SERIES "FRONTLINE" HAS RELEASED A NEW DOCUMENTARY THAT FOLLOWS 3-KIDS AS THEY GROW TO ADULTHOOD AMID THE REALITIES OF GROWING UP "POOR" IN AMERICA.

THE FILM IS TITLED, "BORN POOR.AND THE FILM'S "PRODUCER" IS LAUREN MUCCIOLO, WHO IS ALSO WITH THE HOWARD CENTER FOR INVESTIGATIVE JOURNALISM AT ASU CRONKITE SCHOOL OF JOURNALISM.

GOOD TO SEE YOU, THANK YOU FOR JOINING US.

>> THANK YOU.

>> BORN POOR WAS FILMED OVER 14 YEARS.

>> THIS WAS THE FIRST PROJECT I WORKED ON FOR FRONT LINE, GOING BACK TO 2011.

WE FOUND THEIR STORIES.

FRONT LINE RELEASED SEVERAL FILMS POOR KIDS AND AN UPDATE THIS IS THE FIRST TIME YOU SEE IT TOGETHER.

>> WHEN WE MET THEM THEY LIVED IN THE QUAD CITY.

>> INTERESTING.

>> WAS FOLLOWING THIS ORIGINALLY PLANNED.

>> WE FILMED THEM OVER A LONG PERIOD OF TIME.

WE INVESTED TIME GETTING TO KNOW THEIR WORLD WE SAID WE WOULD COME BACK.

WE STAYED IN TOUCH AND FASCINATING TO HEAR WHAT WAS GOING ON.

FRONT LINE EXPRESSED INTEREST AND HOW IT EFFECTS ACROSS GENERATIONS.

>> HOW DO THEY CHANGE FROM GOING TO CHILDHOOD TO TEEN YEARS.

>> THE TIME PERIOD IS 2012 TO 2017.

YOU HAVE THE END OF THE OBAMA YEARS.

YOU HAVE A LOT HAPPENING IN THE ECONOMY.

COVID-19 HASN'T HAPPENED YET.

THESE KIDS, YOU KNOW, THEY REMAINED INCREDIBLY INSIGHTFUL AND THOUGHTFUL ABOUT THEIR EXPERIENCES.

FROM CHILDHOOD INTO TEEN YEARS AND POVERTY, THEY DEFINITELY ENCOUNTERED BULLYING AND CHALLENGES THAT MADE TEEN YEARS HARD.

>> AND THEN CHALLENGES THERE.

>> YEAH, BETWEEN THE TIME WE LEFT THEM IN 2017 AND PICKED UP WITH THEM AGAIN IN 2024, EACH OF THEM HAD COMPLETED HIGH SCHOOL OR GOTTEN THEIR GED AND SOME STARTED FAMILIES AND EMBARKED ON THEIR CAREER.

>> WE WATCH THE PROSPECTIVE CHANGE AND GROW OVER THE YEARS.

WHAT DOES THAT ADD TO THE CONVERSATION AND KNOWLEDGE OF GROWING UP PEER.

>> ONE THING THAT IS INSIGHTFUL IS HERING THE CHILDREN TALK ABOUT, AS ADULTS, THE RETROSPECTIVE LOOK AT THEIR OWN LIVES AND BEING INTRASPECTIVE AND LOOKING AT THEIR LIVES AND ASK DID I REPEAT THE MISTAKING OF MY MOM AND DAD AND THINGS I LEARNED FROM THE WAY I WAS BROUGHT UP AND I'M DOING WITH MY CHILDREN.

IT WAS INCREDIBLY, IT US WAS INCREDIBLY MOVING AND POWERFUL TO SEE THEM GO THROUGH AND THINK THROUGH THEIR EMOTIONS AND TALK ABOUT MENTAL HEALTH.

NO ONE TALKS ABOUT THAT.

VERY RARELY DO YOU HEAR ABOUT THE MENTAL HEALTH CHALLENGES OF GROWING UP POOR.

WHAT THAT DOES TO YOU AND IN A SENSE OF TRAUMA.

IT'S LIKE A PTSD.

>> IT'S THE LASTING IMPACT OF BEING POOR.

IS THERE PROMISE NOW?

ARE THEY OPTIMISTIC ALSO ADULTS?

>> YOU KNOW, THAT'S AN INCREDIBLE THING ABOUT THESE YOUNG PEOPLE.

THEY HAVE, I THINK, DEVELOPED A BEAUTIFUL RELATIONSHIP.

THEY HAVE HOPE.

THEY KNOW THE IMPORTANCE OF HOPE.

THEY STILL DREAM.

THEY ARE ALSO AWARE OF THE CHALLENGES AND ADVERSITY THEY ARE EXPERIENCING.

YOU SEE, OVER THE COURSE OF THE FILM, THEY EACH HAVE HAD UPS AND DOWNS.

THEY HAD MOMENTS WHERE THINGS WERE TURNING AROUND AND THEY ALSO ALL EXPERIENCED SOME KIND OF TRAGEDY OR HAD TO OVERCOME SOME KIND OF ADVERSITY THAT MADE IT AN OBSTACLE.

>> WITH THAT IN MIND.

WE HAVE A MINUTE OR SO LEFT HERE.

WHAT WOULD ENCOURAGE YOU THE MOST.

WHAT CONCERNS YOU THE MOST SEEING THEM BECOME OLDER FOLKS?

>> I'M THINKING ABOUT THEIR KIDS NOW.

I'M THINKING ABOUT SEEING THEIR KIDS AND NEXT TIME WE MEET THEM WHICH IS PROBABLY FILMING WITH THEM FIVE YEARS FROM NOW.

>> GOOD.

GOOD.

>> THEIR KIDS WOULD BE THE AGE WE MET THEM AT.

SEEING THOSE KIDS AND THAT GENERATION AND HOW THEY EXPERIENCE LIFE AND WHAT THEIR THOUGHTS ARE.

I'M EXCITED TO SEE THAT.

>> LAUREN MUCCIOLO, THE FILM IS BORN BOOR.

THROUGH THAT PARTICULAR PRISM WE LOOK AT KIDS THAT GREW UP POOR.

>> THANK YOU SO MUCH.

>> I'M TED SIMONS.

THANK YOU FOR JOINING US.

HAVE A GREAT