This season features 20 exciting new guests who are game-changers in their fields, with family histories that illustrate the power and diversity of the human experience. Among them are actors Glenn Close, John Lithgow, Jane Lynch, Audra MacDonald, Christopher Meloni and Tony Shalhoub; acclaimed musicians Clint Black, Rosanne Cash and Pharrell Williams; groundbreaking directors Kasi Lemmons and John Waters; renowned journalists Erin Burnett and Nina Totenberg; hilarious comedians Lewis Black and Jim Gaffigan; popular late night personality Andy Cohen; and more to be announced.