Mr. R. D. Carpenter December 15, 1969
R.J. Reynolds Biological Research Program.
I met Dr. Price from R. J. Reynolds at the CTR-USA meeting of December 11 and
12, 1969. He mentioned doing chronic cigarette smoke exposure studies with
rats. The animals received up to 500 cigarettes and emphysema was produced.
They were also looking for other changes but apparently were not successful.
He expressed interest in nicotine pharmacology and mentioned that this work is
integrated with their packaging toxicity work. Recently they hired a wife of
an instructor from Bowman Gray School of Medicine, she is doing research with
lung macrophages. I believe her name is Hess.
He was interested in learning about the gas chromatographic profile of
cigarette smoke within animal exposure chambers.
cc: Dr. T.S. Osdene
Dr. H. Wakeham
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